Board Certified and Trusted Reproductive Medicine Specialist

Dr. Bradley Miller is a Reproductive Endocrinologist who has been in practice for 18 years. Throughout his career over 2,000 babies have been born as a result of his care. He is the Managing Partner at Reproductive Medicine Associates of Michigan, one of the leading fertility centers in Michigan. Learn more about Dr. Miller and follow his blog to discover more answers to your infertility needs and questions.

Archive for October, 2012

Vitrification Improves Success Rates of Frozen Transfers

Thursday, October 25th, 2012

In the past, pregnancy rates have been higher with fresh embryos rather than frozen but now it appears that may not always be the case. During a typical fresh IVF cycle we superovulate the patient with medication that will make her produce multiple eggs. These medications that are used to help a woman grow follicles can also harm the uterine lining so it is not in optimal shape for implantation. Studies have shown that implantation rates are higher in natural cycles rather than superovulated cycles when the embryos are of the same quality. That is why patients may be better off transferring frozen embryos, so that the uterine lining is in a more normal condition making it more receptive for implantation.

Previously, the technique used for freezing embryos was the slow freezing protocol. This was not very efficient and many embryos would get damaged while freezing and thawing. Even the best labs had poor survival rates. It damaged blastomeres because ice crystals formed within the cells and the cryoprotectant chemicals could not consistently prevent this damage. Today, using vitrification, a specialized freezing technique, which freezes the EMBRYO so quickly, ice crystals don’t have time to form, survival rates are better than 98%. Vitrification has allowed us to reduce the number of embryos being transferred because we now know that the embryos that were frozen are in good condition.

If you have any questions please feel free to contact Dr. Brad Miller at (248) 619-3100.